资源类型

期刊论文 132

年份

2023 7

2022 12

2021 11

2020 13

2019 12

2018 9

2017 6

2016 8

2015 6

2014 4

2013 4

2012 3

2011 1

2010 6

2009 5

2008 9

2007 11

2006 1

2005 2

展开 ︾

关键词

COVID-19 2

SARS-CoV-2 2

中药 2

代谢组学 2

多囊卵巢综合征 2

有效性 2

H7N9 1

REC114 1

ZNF438 1

丁酸 1

三向受力状态 1

三维守恒 1

上下图模型 1

不孕症 1

不等围压 1

严重急性呼吸综合征冠状病毒2 1

中医方证代谢组学 1

中国 1

中国队列 1

展开 ︾

检索范围：

排序： 展示方式：

Differential diagnosis of cervical nerve compression syndrome of the external intervertebral foramen

WANG Jinwu, NI Weifeng, XU Jianguang, ZHU Haibo, GUO Shangchun, ZENG Bingfang, ZHAO Binghui

《医学前沿（英文）》 2007年 第1卷 第2期   页码 177-180 doi: 10.1007/s11684-007-0033-3

摘要： The aim of the present research is to study the mechanism of cervical nerve compression syndrome of the external intervertebral foramen and its differential diagnosis with cervical spondylosis. Diagnostic treatment with muscle relaxant, vasodilator, neurotrophic medicine and celecoxib (COX)-2 inhibitor were performed in 20 patients with cervical nerve compression syndrome of the external intervertebral foramen and 20 patients with cervical spondylosis confirmed by operation. Diagnostic local block therapy was performed additionally in cases showing little effect after diagnostic treatment. All the patients were followed up postoperatively for more than one year. Fifteen cases with cervical nerve compression syndrome of the external intervertebral foramen were healed by the diagnostic treatment. The other five cases had a short-term remission and there was no recurrence after diagnostic local block therapy. Diagnostic treatment led to short-term alleviation of the symptom in 20 cases with cervical spondylosis confirmed by operation, the results of which was far from satisfactory and operation was undertaken finally in all the 20 cases. The etiology of cervical nerve compression syndrome of the external intervertebral foramen lies in the compression of the cervical plexus, brachial plexus and cervical dorsal rami by the tendinous decussating fibers of the scalenus anticus, medius, minimus and the posterior muscles of the neck. Diagnostic treatment was propitious to differentiate cervical nerve compression syndrome of the external intervertebral foramen from cervical spondylosis.

关键词： satisfactory     COX     minimus     operation     compression syndrome    

HTML PDF 收藏

Primary spinal epidural non-Hodgkin’s lymphoma presented with spinal cord compression syndrome

Chunquan CAI MD, PhD, Qingjiang ZHANG BM, Changhong SHEN MD, PhD,

《医学前沿（英文）》 2009年 第3卷 第4期   页码 499-502 doi: 10.1007/s11684-009-0075-9

摘要： The spinal epidural space is an uncommon presenting site in primary non-Hodgkin’s lymphomas, especially for children. A boy suffered spinal cord compression syndrome caused by primary spinal epidural non-Hodgkin’s lymphoma. Thoracolumbar magnetic resonance imaging (MRI) demonstrated an intraspinal mass. An operation was performed with gross total tumor removal. Histological examination revealed a non-Hodgkin’s B-cell lymphoma. Bone marrow aspiration was negative for lymphoma involvement. No other therapies (chemotherapy and/or radiotherapy) were performed according to the parents’ opinion. The patient died approximately one year after the operation due to brain metastases. The clinical course and imaging features were discussed with a review of literatures.

关键词： non-Hodgkin’     s lymphoma     primary     spinal cord compression syndrome     epidural space    

HTML PDF 收藏

Influence of steel corrosion on axial and eccentric compression behavior of coral aggregate concrete

《结构与土木工程前沿（英文）》 2021年 第15卷 第6期   页码 1415-1425 doi: 10.1007/s11709-021-0786-9

摘要： To study the behavior of coral aggregate concrete (CAC) column under axial and eccentric compression, the compression behavior of CAC column with different types of steel and initial eccentricity (ei) were tested, and the deformation behavior and ultimate bearing capacity (Nu) were studied. The results showed that as the ei increases, the Nu of CAC column decreases nonlinearly. Besides, the steel corrosion in CAC column is severe, which reduces the steel section and steel strength, and decreases the Nu of CAC column. The durability of CAC structures can be improved by using new organic coated steel. Considering the influence of steel corrosion and interfacial bond deterioration, the calculation models of Nu under axial and eccentric compression were presented.

关键词： coral aggregate concrete column     axial compression     eccentric compression     steel corrosion     calculation model    

HTML PDF 收藏

Behavior of dam concrete under biaxial compression-tension and triaxial compression-compression-tension

WANG Huailiang, SONG Yupu

《结构与土木工程前沿（英文）》 2008年 第2卷 第4期   页码 323-328 doi: 10.1007/s11709-008-0043-5

摘要： In order to meet the requirement for nonlinear analysis and design of mass concrete structures, the deformation behavior and strength of three-graded concrete specimens 250 mm × 250 mm × 400 mm with a maximum aggregate size of 80 mm and the corresponding wet-screened concrete specimens 150 mm × 150 mm × 300 mm with a maximum aggregate size of 40 mm were studied experimentally. Specimens subjected to biaxial compression-tension (C-T) and triaxial compression-compression-tension (C-C-T) stress states. Test data indicate that both the deformation and strength of the mass concrete specimens are lower than those of the corresponding wet-screened concrete small specimens, but the initial tangent modulus of the stress-strain curve of the former is greater than that of the latter. Test results show that the wet-screened effect and size effect of the specimens under complex stress states are obvious such that these should be considered in the design of mass concrete structures. In addition, respective failure criteria for mass concrete in principal stress space and octahedron stress space are proposed.

关键词： requirement     wet-screened concrete     compression-tension     maximum aggregate     principal    

HTML PDF 收藏

Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational

《医学前沿（英文）》 2022年 第16卷 第4期   页码 651-658 doi: 10.1007/s11684-021-0859-0

摘要： To present the clinical characteristics and the misdiagnosis rate of acute coronary syndrome manifested primarily as throat discomfort, we conducted a multicentric and retrospective study in the cardiology and otorhinolaryngology departments. Records of patients with primary complaint of throat discomfort, absence of chest pain at onset, and an ultimate diagnosis of acute coronary syndrome, as well as patients with pharyngitis (as controls) were collected from May 2015 to April 2016. The patients’ main manifestations were compared. Logistic regression results showed that chest tightness, dyspnea, perspiring, and exertional throat symptoms were significantly associated with acute coronary syndrome, with odds ratios of 8.3 (95% CI 2.2−31.5), 10.9 (95% CI 1.8−66.9), 25.4 (95% CI 3.6−179.9), and 81.2 (95% CI 13.0−506.7). A total of 25 (56.82%) out of 44 acute coronary syndrome patients, who were first admitted to the otorhinolaryngology department, were misdiagnosed, with a 12% (3/25) mortality rate. Throat discomfort can be the principal manifestation of acute coronary syndrome. Such patients exhibit high misdiagnosis and mortality rates. Exertional throat symptoms, chest tightness, perspiring, and dyspnea were important indicators of acute coronary syndrome in patients whose main complaint was throat discomfort. The awareness of this condition will result in prompt diagnosis and reduce morbidity and mortality.

关键词： acute coronary syndrome (ACS)     throat discomfort (TD)     throat pain     cardiology departments     non-cardiologic physicians    

HTML PDF 收藏

Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience

null

《医学前沿（英文）》 2014年 第8卷 第4期   页码 419-426 doi: 10.1007/s11684-014-0383-6

摘要：

Aneurysmal dilatation of the aortic sinuses of Valsalva has been most extensively documented in the setting of aortopathies, particularly Marfan syndrome. On the other hand, there is limited data in the literature about congenital sinus of Valsalva aneurysms outside this context. For the purpose of this review, we carried out a literature search on aneurysmal dilatation of the sinuses of Valsalva in Marfan syndrome, and compared this with congenital sinus of Valsalva aneurysms, also including data from a case series from our institution. In conclusion, there are differences in management of aortic dilatation in Marfan syndrome and congenital sinus of Valsalva aneurysms. Though less well-recognised, congenital aneurysms are often associated with significant morbidity and mortality and timely intervention is necessary.

关键词： sinus of Valsalva aneurysms     Marfan syndrome     aortic dissection    

HTML PDF 收藏

Effects of compression ratio on the combustion characteristics of a homogeneous charge compression ignition

SONG Ruizhi, ZHOU Longbao, LIU Shenghua, LI Wei, HU Tiegang

《能源前沿（英文）》 2007年 第1卷 第4期   页码 463-467 doi: 10.1007/s11708-007-0068-0

摘要： The effects of homogeneous charge compression ignition (HCCI) engine compression ratio on its combustion characteristics were studied experimentally on a modified TY1100 single cylinder engine fueled with dimethyl ether. The resul

关键词： homogeneous     cylinder     combustion     compression     dimethyl    

HTML PDF 收藏

Numerical study of ignition mechanism of n-heptane direct injection compression-ignition engine

Xiaoping GUO, Zhanjie WANG,

《能源前沿（英文）》 2009年 第3卷 第4期   页码 432-439 doi: 10.1007/s11708-009-0050-9

摘要： A detailed chemical dynamical mechanism of oxidation of n-heptane was implemented into kiva-3 code to study the ignition mechanism of a high-temperature, high-pressure, three-dimensional-space, transient turbulent, non-homogeneous, mono-component fuel in the engine. By testing the quantity of the heat released by the chemical reaction within the cylinder cell, the elementary reaction showing an obvious increase in the cell temperature was defined as ignition reaction and the corresponding cell as ignition position. The main pathway of the ignition reaction was studied by using the reverse deducing method. The result shows that the ignition in the engine can be divided into low-temperature ignition and high-temperature ignition, both of which follow the same rule in releasing heat, called the impulse heat releasing feature. Low-temperature ignition reaction, whose ignition reaction is c5h9o1-4=ch3cho+c3h5-a, follows the oxidation mechanism, while high-temperature ignition reaction, whose ignition reaction is c2h3o1-2=ch3co, follows the decomposition mechanism. No matter which ignition it is in, the chemical reaction that restrains the ignition reaction from lasting is the deoxidization reaction of alkylperoxy radicals.

关键词： compression-ignition engine     ignition mechanism     elementary reaction     n-heptane    

HTML PDF 收藏

Lung transplantation for bronchiolitis obliterans syndrome after allogenic hematopoietic stem cell transplantation

null

《医学前沿（英文）》 2018年 第12卷 第2期   页码 224-228 doi: 10.1007/s11684-017-0538-3

摘要：

Bronchiolitis obliterans syndrome (BOS) after hematopoietic stem cell transplantation (HSCT) is a major cause of morbidity and mortality with limited treatment options. Lung transplantation (LTX) has been rarely reported as a treatment option for selected HSCT recipients with this problem. In the present study, we reported six patients who underwent LTX due to BOS after HSCT (two females, four males) from January 2012 to December 2014 in our center. The median time from HSCT to diagnosis of BOS was 2.5 years (ranging from 1 to 5 years). At a median time of 4 years (ranging from 2 to 5 years) after diagnosis of BOS, four patients received bilateral sequential LTX, and two patients received single LTX. One of the recipients suffered from mild acute rejection after LTX, another suffered from primary lung graft dysfunction on post-operation day 2, and three experienced fungal infections. The median time for follow-up after LTX was 19.5 months (ranging from 12 to 39 months). At present, all patients are alive with good functional capacity and no relapse of BOS and hematologic malignancy conditions. Patients who received bilateral LTX have better pulmonary functions than patients who received single LTX.

关键词： bronchiolitis obliterans syndrome (BOS)     hematopoietic stem cell transplantation (HSCT)     lung transplantation (LTX)    

HTML PDF 收藏

Three-dimensional numerical simulation for plastic injection-compression molding

Yun ZHANG, Wenjie YU, Junjie LIANG, Jianlin LANG, Dequn LI

《机械工程前沿（英文）》 2018年 第13卷 第1期   页码 74-84 doi: 10.1007/s11465-018-0490-1

摘要：

Compared with conventional injection molding, injection-compression molding can mold optical parts with higher precision and lower flow residual stress. However, the melt flow process in a closed cavity becomes more complex because of the moving cavity boundary during compression and the nonlinear problems caused by non-Newtonian polymer melt. In this study, a 3D simulation method was developed for injection-compression molding. In this method, arbitrary Lagrangian-Eulerian was introduced to model the moving-boundary flow problem in the compression stage. The non-Newtonian characteristics and compressibility of the polymer melt were considered. The melt flow and pressure distribution in the cavity were investigated by using the proposed simulation method and compared with those of injection molding. Results reveal that the fountain flow effect becomes significant when the cavity thickness increases during compression. The back flow also plays an important role in the flow pattern and redistribution of cavity pressure. The discrepancy in pressures at different points along the flow path is complicated rather than monotonically decreased in injection molding.

关键词： injection-compression molding     simulation     injection molding     melt flow     cavity pressure    

HTML PDF 收藏

Genetic basis of adult-onset nephrotic syndrome and focal segmental glomerulosclerosis

null

《医学前沿（英文）》 2017年 第11卷 第3期   页码 333-339 doi: 10.1007/s11684-017-0564-1

摘要：

Nephrotic syndrome (NS) is one of the most common glomerular diseases with signs of nephrosis, heavy proteinuria, hypoalbuminemia, and edema. Dysfunction of glomerular filtration barrier causes protein loss through the kidneys. Focal segmental glomerulosclerosis (FSGS) accounts for nearly 20% of NS among children and adults. Adult-onset FSGS/NS is often associated with low response to steroid treatment and immunosuppressive medication and poor renal survival. Several genes involved in NS and FSGS have been identified by linkage analysis and next-generation sequencing. Most of these genes encode proteins and are highly expressed in glomerular podocytes, which play crucial roles in slit-diaphragm signaling, regulation of actin cytoskeleton dynamics and maintenance of podocyte integrity, and cell–matrix interactions. In this review, we focus on the recently identified genes in the adult-onset NS and FSGS and discuss clinical significance of screening of these genes.

关键词： nephrotic syndrome     focal segmental glomerulosclerosis     genetic    

HTML PDF 收藏

Cushing’s syndrome during pregnancy caused by adrenal cortical adenoma: a case report and literature

null

《医学前沿（英文）》 2015年 第9卷 第3期   页码 380-383 doi: 10.1007/s11684-015-0407-x

摘要：

Cushing’s syndrome (CS) during pregnancy is a rare condition with significant maternal and fetal complications. A case of CS during the third trimester of pregnancy secondary to adrenocortical adenoma was reported. Literature review revealed the disadvantages of different treatments in this period. Besides the conservative treatment, surgery is recommended for CS during the third trimester of pregnancy secondary to adrenal adenoma, if an experienced surgeon is available.

关键词： Cushing’s syndrome     pregnancy     adrenocortical adenoma    

HTML PDF 收藏

Familial amyloid cardiomyopathy masquerading as chronic Guillain-Barre syndrome: things are not always

null

《医学前沿（英文）》 2017年 第11卷 第2期   页码 293-296 doi: 10.1007/s11684-017-0516-9

摘要：

Familial amyloid cardiomyopathy is a challenging condition that mimics many other diseases, particularly in patients with pronounced neurological presentations and unexplained or equivocal cardiac abnormalities. In this case, a 57-year-old man was admitted for outpatient cardiological evaluation of progressive right heart failure and limb paraesthesias. The patient presented with hypertension, chronic Guillain-Barre syndrome, and sick sinus syndrome. Transthoracic echocardiograms showed a thickened ventricular wall and enlarged atrium. Tissue Doppler showed a restrictive filling pattern. Transthyretin (TTR)-associated amyloidosis, which was revealed by abdominal fat-pad biopsy and DNA analysis, explained the concurrence of independent pathological features, including neuropathy and cardiac involvement. Genetic testing identified a G>T mutation in exon 4 of the transthyretin (TTR) gene. This mutation resulted in the alanine-to-serine substitution at amino acid position 117. Moreover, genetic testing confirmed that the patient’s asymptomatic son carried the same amyloidogenic TTR mutation. Given these findings, the diagnosis of familial amyloid cardiomyopathy, which was misdiagnosed as chronic Guillain-Barre syndrome, was proposed.

关键词： transthyretin (TTR) cardiac amyloidosis     sick sinus syndrome     chronic Guillain-Barre syndrome    

HTML PDF 收藏

Improvement of engine performance with high compression ratio based on knock suppression using Miller

Haiqiao WEI, Jie YU, Lei ZHOU

《能源前沿（英文）》 2019年 第13卷 第4期   页码 691-706 doi: 10.1007/s11708-019-0621-3

摘要： In theory, high compression ratio has the potential to improve the thermal efficiency and promote the power output of the SI engine. However, the application of high compression ratio is substantially limited by the knock in practical working process. The objective of this work is to comprehensively investigate the application of high compression ratio on a gasoline engine based on the Miller cycle with boost pressure and split injection. In this work, the specific optimum strategies for CR10 and CR12 were experimentally investigated respectively on a single cylinder DISI engine. It was found that a high level of Miller cycle with a higher boost pressure could be used in CR12 to achieve an effective compression ratio similar to CR10, which could eliminate the knock limits at a high compression ratio and high load. To verify the advantages of the high compression ratio, the fuel economy and power performance of CR10 and CR12 were compared at full and partial loads. The result revealed that, compared with CR10, a similar power performance and a reduced fuel consumption of CR12 at full load could be achieved by using the strong Miller cycle and split injection. At partial load, the conditions of CR12 had very superior fuel economy and power performance compared to those of CR10.

关键词： high compression ratio     knock     Miller cycle     split injection     engine performance    

HTML PDF 收藏

Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns

null

《医学前沿（英文）》 2016年 第10卷 第2期   页码 111-119 doi: 10.1007/s11684-016-0446-y

摘要：

The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 brought back memories of the occurrence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002. More than 1500 MERS-CoV cases were recorded in 42 months with a case fatality rate (CFR) of 40%. Meanwhile, 8000 cases of SARS-CoV were confirmed in six months with a CFR of 10%. The clinical presentation of MERS-CoV ranges from mild and non-specific presentation to progressive and severe pneumonia. No predictive signs or symptoms exist to differentiate MERS-CoV from community-acquired pneumonia in hospitalized patients. An apparent heterogeneity was observed in transmission. Most MERS-CoV cases were secondary to large outbreaks in healthcare settings. These cases were secondary to community-acquired cases, which may also cause family outbreaks. Travel-associated MERS infection remains low. However, the virus exhibited a clear tendency to cause large outbreaks outside the Arabian Peninsula as exemplified by the outbreak in the Republic of Korea. In this review, we summarize the current knowledge about MERS-CoV and highlight travel-related issues.

关键词： coronavirus     MERS     Middle East respiratory syndrome    

HTML PDF 收藏

标题 作者 时间 类型 操作

Differential diagnosis of cervical nerve compression syndrome of the external intervertebral foramen

WANG Jinwu, NI Weifeng, XU Jianguang, ZHU Haibo, GUO Shangchun, ZENG Bingfang, ZHAO Binghui

期刊论文

Primary spinal epidural non-Hodgkin’s lymphoma presented with spinal cord compression syndrome

Chunquan CAI MD, PhD, Qingjiang ZHANG BM, Changhong SHEN MD, PhD,

期刊论文

Influence of steel corrosion on axial and eccentric compression behavior of coral aggregate concrete

期刊论文

Behavior of dam concrete under biaxial compression-tension and triaxial compression-compression-tension

WANG Huailiang, SONG Yupu

期刊论文

Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational

期刊论文

Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience

null

期刊论文

Effects of compression ratio on the combustion characteristics of a homogeneous charge compression ignition

SONG Ruizhi, ZHOU Longbao, LIU Shenghua, LI Wei, HU Tiegang

期刊论文

Numerical study of ignition mechanism of n-heptane direct injection compression-ignition engine

Xiaoping GUO, Zhanjie WANG,

期刊论文

Lung transplantation for bronchiolitis obliterans syndrome after allogenic hematopoietic stem cell transplantation

null

期刊论文

Three-dimensional numerical simulation for plastic injection-compression molding

Yun ZHANG, Wenjie YU, Junjie LIANG, Jianlin LANG, Dequn LI

期刊论文

Genetic basis of adult-onset nephrotic syndrome and focal segmental glomerulosclerosis

null

期刊论文

Cushing’s syndrome during pregnancy caused by adrenal cortical adenoma: a case report and literature

null

期刊论文

Familial amyloid cardiomyopathy masquerading as chronic Guillain-Barre syndrome: things are not always

null

期刊论文

Improvement of engine performance with high compression ratio based on knock suppression using Miller

Haiqiao WEI, Jie YU, Lei ZHOU

期刊论文

Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns

null

期刊论文